Isolation and initial propagation of guinea pig adenovirus (GPAdV) in Cavia porcellus cell lines [version 2; peer review: 2 approved]
Background: The lack of adequate in vitro systems to isolate and propagate guinea pig adenovirus (GPAdV), a prevalent cause of respiratory illness of varaible severity in laboratory guinea pig colonies worldwide, has precluded its formal characterization to allow for the development of comprehensive diagnostic assays, and for the execution of compl